Optimal Amount of Basic Fibroblast Growth Factor in Gelatin Sponges Incorporating β-Tricalcium Phosphate with Chondrocytes
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چکیده
منابع مشابه
Enhanced intestinal anastomotic healing with gelatin hydrogel incorporating basic fibroblast growth factor.
Anastomotic leakage is a common complication of intestinal surgery. In an attempt to resolve this issue, a promising approach is enhancement of anastomotic wound healing. A method for controlled release of basic fibroblast growth factor (bFGF) using a gelatin hydrogel was developed with the objective of investigating the effects of this technology on intestinal anastomotic healing. The small in...
متن کاملEffect of Control-released Basic Fibroblast Growth Factor Incorporated in β-Tricalcium Phosphate for Murine Cranial Model
BACKGROUND β-Tricalcium phosphate (β-TCP) is used clinically as a bone substitute, but complete osteoinduction is slow. Basic fibroblast growth factor (bFGF) is important in bone regeneration, but the biological effects are very limited because of the short half-life of the free form. Incorporation in gelatin allows slow release of growth factors during degradation. The present study evaluated ...
متن کاملGelatin sheet incorporating basic fibroblast growth factor enhances healing of devascularized sternum in diabetic rats.
BACKGROUND Poor healing of the sternum often limits the use of bilateral internal thoracic arteries (BITAs) after coronary bypass surgery in diabetic patients. We have reported that a gelatin sheet that incorporates basic fibroblast growth factor (bFGF) accelerates sternal healing after BITA removal in normal rats. This study evaluated the effects of the above method for sternal healing in diab...
متن کاملBasic fibroblast growth factor increases IFT88 expression in chondrocytes
Intraflagellar transport protein 88 (IFT88) is protein crucial for the assembly and maintenance of primary cilia in chondrocytes. Primary cilia regulate mechanical and chemical signals in chondrocytes; however, the effects of cytokines on IFT88 expression and cilia formation and maintenance remain to be elucidated. Therefore, the role of basic fibroblast growth factor (bFGF) on IFT88 expression...
متن کاملEffect of basic fibroblast growth factor (FGF-2) in combination with beta tricalcium phosphate on root coverage in dog.
OBJECTIVE In root coverage treatment, periodontal regeneration in gingival recession-type defects is an important challenge for the periodontist. The aim of this study was to histometrically investigate the effect of combined use of basic fibroblast growth factor (FGF-2) and beta tricalcium phosphate (β-TCP) on root coverage in dogs. MATERIALS AND METHODS Sixteen adult beagle dogs were used. ...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2015
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2013.0655